Active regulatory elements recruit cohesin to establish cell specific chromatin domains

Active regulatory elements recruit cohesin to establish cell specific chromatin domains

Abstract As the 3D structure of the genome is analysed at ever increasing resolution it is clear that there is considerable variation in the 3D chromatin architecture across different cell types. It has been proposed that this may, in part, be due to increased recruitment of cohesin to activated cis...

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Main Authors: Emily Georgiades, Caroline Harrold, Nigel Roberts, Mira Kassouf, Simone G. Riva, Edward Sanders, Damien Downes, Helena S. Francis, Joseph Blayney, A. Marieke Oudelaar, Thomas A. Milne, Douglas Higgs, Jim R. Hughes
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-96248-4
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https://doi.org/10.1038/s41598-025-96248-4

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