Creation of human/mouse mitochondrial chimera model carrying A3243G mutation and exploring pathogenesis of mtDNA A3243G in vivo

Generation of chimera mice with human mitochondria carrying A3243G mutation by microinjection technique could provide an ideal model for studying how xeno-mitochondrial DNA is transmitted to following generations and distributed in various tissues and exploring the effect of A 3243G mutation on mito...

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Bibliographic Details
Main Authors: LI Ji-xia, WANG Ju, LIU Yi-nong
Format: Article
Language:English
Published: Zhejiang University Press 2008-11-01
Series:浙江大学学报. 农业与生命科学版
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Online Access:https://www.academax.com/doi/10.3785/j.issn.1008-9209.2008.06.006
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