Methodological approach for allele-specific antibody responses to HEK-293T-based cell lines expressing single MHC class I chain-related gene B antigens

Methodological approach for allele-specific antibody responses to HEK-293T-based cell lines expressing single MHC class I chain-related gene B antigens

Abstract Background Antibodies against non-HLA antigens, such as MICA and MICB, have emerged as potential contributors to antibody-mediated rejection and graft failure. While MICA antibodies are well characterized, MICB-specific antibodies remain poorly understood due to the lack of standardized det...

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Bibliographic Details
Main Authors: Ji-Ho Jeon, Cheol-Hwa Hong, You-Seok Hyun, Hyeyoung Lee, Eun-Jee Oh, Tai-Gyu Kim, In-Cheol Baek
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Molecular and Cell Biology
Subjects:
MHC class I chain-related gene B
MICB antibody
Allotype response
Panel reactive antibody test
Kidney transplant
Online Access:https://doi.org/10.1186/s12860-025-00549-5
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https://doi.org/10.1186/s12860-025-00549-5

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