Microglia-driven inflammation induces progressive tauopathies and synucleinopathies

Abstract Alzheimer’s disease and Parkinson’s disease are characterized by distinct types of abnormal protein aggregates within neurons. These aggregates are known as neurofibrillary tangles and Lewy bodies, which consist of tau and α-synuclein, respectively. As the diseases progress, these aggregate...

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Bibliographic Details
Main Authors: Sang Hwan Lee, Eun-Jin Bae, Sung Jun Park, Seung-Jae Lee
Format: Article
Language:English
Published: Nature Publishing Group 2025-05-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-025-01450-z
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