Tension at the gate: sensing mechanical forces at the blood–brain barrier in health and disease
Abstract Microvascular brain endothelial cells tightly limit the entry of blood components and peripheral cells into the brain by forming the blood–brain barrier (BBB). The BBB is regulated by a cascade of mechanical and chemical signals including shear stress and elasticity of the adjacent endothel...
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Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-12-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12974-024-03321-2 |
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