Effect of mosquito saliva from distinct species on human dermal endothelial cell function in vitro and West Nile virus pathogenesis in vivo

Effect of mosquito saliva from distinct species on human dermal endothelial cell function in vitro and West Nile virus pathogenesis in vivo

During probing and feeding, an infected mosquito injects both virus and saliva into the host skin. The presence of mosquito saliva in the skin increases arbovirus pathogenesis in the bitten host, however the exact mechanism behind this remains to be determined. It is hypothesized that disease enhanc...

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Bibliographic Details
Main Authors: Imke Visser, Vincent Vaes, Peter van Run, Eleanor M. Marshall, Lars Vermaat, Charlotte Linthout, Dick H.W. Dekkers, Jeroen A.A. Demmers, Marion P.G. Koopmans, Constantianus J.M. Koenraadt, Melanie Rissmann, Barry Rockx
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Emerging Microbes and Infections
Subjects:
Arbovirus
Culex pipiens
mosquito saliva
pathogenesis
transmission
vascular leakage
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2025.2502006
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https://www.tandfonline.com/doi/10.1080/22221751.2025.2502006

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