An in vivo systemic massively parallel platform for deciphering animal tissue-specific regulatory function

An in vivo systemic massively parallel platform for deciphering animal tissue-specific regulatory function

Introduction: Transcriptional regulation is an important process wherein non-protein coding enhancer sequences play a key role in determining cell type identity and phenotypic diversity. In neural tissue, these gene regulatory processes are crucial for coordinating a plethora of interconnected and r...

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Main Authors: Ashley R. Brown, Grant A. Fox, Irene M. Kaplow, Alyssa J. Lawler, BaDoi N. Phan, Lahari Gadey, Morgan E. Wirthlin, Easwaran Ramamurthy, Gemma E. May, Ziheng Chen, Qiao Su, C. Joel McManus, Robert van de Weerd, Andreas R. Pfenning
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Genetics
Subjects:
machine learning
aav
in vivo
enhancer
PHP.eB
brain
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1533900/full
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https://www.frontiersin.org/articles/10.3389/fgene.2025.1533900/full

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