Machine learning-based drug-drug interaction prediction: a critical review of models, limitations, and data challenges

Background/ObjectivesNew computational methods, based on statistical, machine learning, and deep learning techniques using drug-related entities (e.g., genes, protein bindings, etc.), help reduce the costs of in-vitro experiments through drug-drug interaction prediction (DDIp). This review examines...

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Bibliographic Details
Main Authors: Flaviu-Ioan Gheorghita, Vlad-Ioan Bocanet, Laszlo Barna Iantovics
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1632775/full
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