Structural basis for Rab6 activation by the Ric1-Rgp1 complex

Abstract Rab GTPases act as molecular switches to regulate organelle homeostasis and membrane trafficking. Rab6 plays a central role in regulating cargo flux through the Golgi and is activated via nucleotide exchange by the Ric1-Rgp1 protein complex. Ric1-Rgp1 is conserved throughout eukaryotes but...

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Bibliographic Details
Main Authors: J. Ryan Feathers, Ryan C. Vignogna, J. Christopher Fromme
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54869-9
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