Gut microbiota composition as a candidate risk factor for dimethyl fumarate-induced lymphopenia in multiple sclerosis

Gut microbiota composition as a candidate risk factor for dimethyl fumarate-induced lymphopenia in multiple sclerosis

Mounting evidence points towards a pivotal role of gut microbiota in multiple sclerosis (MS) pathophysiology. Yet, whether disease-modifying treatments alter microbiota composition and whether microbiota shape treatment response and side-effects remain unclear. In this prospective observational pilo...

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Main Authors: Martin Diebold, Marco Meola, Srinithi Purushothaman, Lena K Siewert, Elisabeth Pössnecker, Tim Roloff, Raija LP Lindberg, Jens Kuhle, Ludwig Kappos, Tobias Derfuss, Adrian Egli, Anne-Katrin Pröbstel
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Gut Microbes
Subjects:
Multiple sclerosis
microbiome
dimethyl fumarate
lymphopenia
metabolomics
therapeutic biomarker
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2022.2147055
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https://www.tandfonline.com/doi/10.1080/19490976.2022.2147055

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