Effect of an eight-week high-intensity interval training programme on circulating sphingolipid levels in middle-aged adults at elevated cardiometabolic risk (SphingoFIT)-Protocol for a randomised controlled exercise trial.

<h4>Introduction</h4>Evidence indicates that sphingolipid accumulation drives complex molecular alterations promoting cardiometabolic diseases. Clinically, it was shown that sphingolipids predict cardiometabolic risk independently of and beyond traditional biomarkers such as low-density...

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Main Authors: Justin Carrard, Manuel Hofer, Luisa Prechtl, Eva Fleischlin, Manuel Huber, Hector Gallart-Ayala, Tony Teav, Denis Infanger, Christoph Höchsmann, Karsten Koehler, Timo Hinrichs, Henner Hanssen, Julijana Ivanisevic, Arno Schmidt-Trucksäss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0302477
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