Discovery of Z1362873773: a novel fascin inhibitor from a large chemical library for colorectal cancer

Discovery of Z1362873773: a novel fascin inhibitor from a large chemical library for colorectal cancer

Abstract Metastasis is one of the leading causes of cancer-related death worldwide. Fascin, a protein that bundles actin filaments to produce protrusions in cancer cells, plays a significant role in the enhancement of cell migration. This protein has been shown that the overexpression of this protei...

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Main Authors: Alejandro Rodríguez-Martínez, Lucía Giraldo-Ruiz, María C. Ramos, Irene Luque, Diogo Ribeiro, Fátima Postigo-Corrales, Begoña Alburquerque-González, Silvia Montoro-García, Ana Belén Arroyo-Rodríguez, Pablo Conesa-Zamora, Ana María Hurtado, Ginés Luengo-Gil, Horacio Pérez-Sánchez
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-96457-x
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https://doi.org/10.1038/s41598-025-96457-x

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