Expression of the RNA helicase DDX3 and the hypoxia response in breast cancer.

Expression of the RNA helicase DDX3 and the hypoxia response in breast cancer.

<h4>Aims</h4>DDX3 is an RNA helicase that has antiapoptotic properties, and promotes proliferation and transformation. In addition, DDX3 was shown to be a direct downstream target of HIF-1α (the master regulatory of the hypoxia response) in breast cancer cell lines. However, the relation...

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Main Authors: Guus M Bol, Venu Raman, Petra van der Groep, Jeroen F Vermeulen, Arvind H Patel, Elsken van der Wall, Paul J van Diest
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0063548&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0063548&type=printable

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