Influence of race, ethnicity, and sex on the performance of epigenetic predictors of phenotypic traits

Influence of race, ethnicity, and sex on the performance of epigenetic predictors of phenotypic traits

Abstract Background DNA methylation-based predictors of phenotypic traits including leukocyte proportions, smoking activity, biological aging, and circulating levels of plasma proteins are widely used as biomarkers in public health research. However, limited racial and ethnic diversity of research p...

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Main Authors: Dennis Khodasevich, Nicole Gladish, Saher Daredia, Anne K. Bozack, Hanyang Shen, Jamaji C. Nwanaji-Enwerem, Belinda L. Needham, David H. Rehkopf, Andres Cardenas
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Clinical Epigenetics
Subjects:
Epigenetics
Aging
Machine learning
Disparities
Online Access:https://doi.org/10.1186/s13148-025-01864-6
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https://doi.org/10.1186/s13148-025-01864-6

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