Motor protein KIF13B orchestrates hepatic metabolism to prevent metabolic dysfunction-associated fatty liver disease

Motor protein KIF13B orchestrates hepatic metabolism to prevent metabolic dysfunction-associated fatty liver disease

Abstract Background Kinesin family member 13B (KIF13B), a crucial motor protein, exerts multiple cellular biological functions. However, the implication of KIF13B in metabolic dysfunction-associated fatty liver disease (MAFLD) has not been explored yet. This study aimed to investigate KIF13B’s role...

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Main Authors: Guo-Lin Miao, Wen-Xi Zhang, Yi-Tong Xu, Yi-Ran Liu, Ping-Ping Lai, Jia-Bao Guo, Gong-Lie Chen, Jing-Xuan Chen, Zi-Hao Zhou, Yan-Wei Li, Chong Zhang, Yang Ding, Lian-Xin Zhang, Yu-Fei Han, Jin-Xuan Chen, Jing-Dong Wu, Yin-Qi Zhao, Si Mei, Yang Zhao, Yuan-Wu Ma, Ling Zhang, Wei Huang, Dong-Yu Zhao, Er-Dan Dong, Yu-Hui Wang, Xun-De Xian
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Military Medical Research
Subjects:
Kinesin family member 13B
AMP-activated catalytic subunit alpha 1
Mitochondrial homeostasis
Lipid metabolism
Metabolic dysfunction-associated fatty liver disease
Online Access:https://doi.org/10.1186/s40779-025-00594-3
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https://doi.org/10.1186/s40779-025-00594-3

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