Effects of dietary 1,4-dihydropyridine on fatty liver of laying hens

Five hundred and fourty of laying hens at the age of 40 weeks were randomly allotted to 3 groups, each of which included 4 replicates of 45 hens. The groups were fed with a basal corn-soybean diet, supplemented with 0 (control),150 mg/kg, 300 mg/kg 1,4-dihydropyridine. The results indicated that 1,4...

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Bibliographic Details
Main Authors: ZOU Xiao-ting, ZHU Jing-lan, XU Zi-rong
Format: Article
Language:English
Published: Zhejiang University Press 2003-11-01
Series:浙江大学学报. 农业与生命科学版
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Online Access:https://www.academax.com/doi/10.3785/1008-9209.2003.06.0655
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Summary:Five hundred and fourty of laying hens at the age of 40 weeks were randomly allotted to 3 groups, each of which included 4 replicates of 45 hens. The groups were fed with a basal corn-soybean diet, supplemented with 0 (control),150 mg/kg, 300 mg/kg 1,4-dihydropyridine. The results indicated that 1,4-dihydropyridine (DHP) significantly improved laying performance. Supplement of 150 mg/kg and 300 mg/kg DHP to the diet improved daily mean laying rate by 9.39% (P<0.01) and 12.97% (P<0.01), lowered the feed/egg ratio by 9.54% (P<0.05) and 7.25% (P<0.05), decreased percentage of abdominal fat by 35.4% (P<0.05) and 46.9% (P<0.05), and reduced liver fat by 32.4% (P<0.05) and 10.5% (P>0.05), respectively. Also found was that 150 mg/kg and 300 mg/kg DHP increased abdominal fat HSL (hormone sensitive lipase) activity by 39.64% (P<0.05) and 48.48% (P<0.05), decreased LDH (lactic dehydrogenase) activity by 32.94% (P<0.01) and 25.16% (P< 0.05), and decreased AST (aspartic acid transferase) activity by 21.78% (P<0.05) and 7.43% (P> 0.05), respectively. These results indicated that DHP significantly improved laying performance of the treated hens and decreased their percentage of liver fat.
ISSN:1008-9209
2097-5155