Voiding symptom severity varies independently from non-adrenergic prostate smooth muscle contractions in patients undergoing surgery for benign prostatic hyperplasia

Voiding symptom severity varies independently from non-adrenergic prostate smooth muscle contractions in patients undergoing surgery for benign prostatic hyperplasia

BackgroundResistance of voiding symptoms to α1-blockers in benign prostatic hyperplasia (BPH) has been provisionally explained by non-adrenergic prostate smooth muscle contraction. Here, we examined relationships between contractions and voiding symptoms in prostate tissues from laser-enucleation.Me...

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Bibliographic Details
Main Authors: Patrick Keller, Sheng Hu, Philip Nicola, Laurenz Berger, Alexander Tamalunas, Philipp Weinhold, Christian G. Stief, Martin Hennenberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Physiology
Subjects:
benign prostatic hyperplasia (BPH)
voiding symptoms
lower urinary tract symptoms (LUTS)
international prostate symptom score (IPSS)
holmium laser enucleation of the prostate (HoLEP)
smooth muscle contraction
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1612954/full
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https://www.frontiersin.org/articles/10.3389/fphys.2025.1612954/full

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