G6PD deficiency at Sumba in Eastern Indonesia is prevalent, diverse and severe: implications for primaquine therapy against relapsing Vivax malaria.

G6PD deficiency at Sumba in Eastern Indonesia is prevalent, diverse and severe: implications for primaquine therapy against relapsing Vivax malaria.

Safe treatment of Plasmodium vivax requires diagnosis of both the infection and status of erythrocytic glucose-6-phosphate dehydrogenase (G6PD) activity because hypnozoitocidal therapy against relapse requires primaquine, which causes a mild to severe acute hemolytic anemia in G6PD deficient patient...

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Main Authors: Ari Winasti Satyagraha, Arkasha Sadhewa, Vanessa Baramuli, Rosalie Elvira, Chase Ridenour, Iqbal Elyazar, Rintis Noviyanti, Farah Novita Coutrier, Alida Roswita Harahap, J Kevin Baird
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0003602
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https://doi.org/10.1371/journal.pntd.0003602

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