An improved in vitro 3T3-L1 adipocyte model of inflammation and insulin resistance

An improved in vitro 3T3-L1 adipocyte model of inflammation and insulin resistance

Tumor necrosis factor alpha (TNF-α)/hypoxia-treated 3T3-L1 adipocytes have been used to model inflamed and insulin-resistant adipose tissue: this study examines gaps in the model. We tested whether modulating TNF-α/hypoxia treatment time could reduce cell death while still inducing inflammation and...

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Bibliographic Details
Main Authors: Ifeoluwa A. Odeniyi, Bulbul Ahmed, Benjamin Anbiah, Grace Hester, Peter T. Abraham, Elizabeth A. Lipke, Michael W. Greene
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Adipocyte
Subjects:
Adipocyte
inflammation
insulin resistance
in vitro model
3T3-L1 cells
Online Access:https://www.tandfonline.com/doi/10.1080/21623945.2024.2414919
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https://www.tandfonline.com/doi/10.1080/21623945.2024.2414919

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