Low‐Carbohydrate Diet Exacerbates Denervation‐Induced Atrophy of Rat Skeletal Muscle Under the Condition of Identical Protein Intake

Low‐Carbohydrate Diet Exacerbates Denervation‐Induced Atrophy of Rat Skeletal Muscle Under the Condition of Identical Protein Intake

ABSTRACT Background While decreased protein intake is associated with muscle mass loss, it is unclear whether a decrease in carbohydrate intake adversely affects muscle atrophy independently of protein intake. Herein, we examined whether a low‐carbohydrate (low‐CHO) diet exacerbates denervation‐indu...

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Main Authors: Aki Yokogawa, Kohei Kido, Ikuru Miura, Eisuke Oyama, Daisuke Takakura, Keigo Tanaka, Daniel J. Wilkinson, Kenneth Smith, Philip J. Atherton, Kentaro Kawanaka
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
AMPK
Atrogin‐1
deuterium oxide
low‐carbohydrate diet
myofibrillar protein synthesis rate
Online Access:https://doi.org/10.1002/jcsm.13738
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https://doi.org/10.1002/jcsm.13738

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