SREBF1-mediated SND1 transcriptional activation promotes prostate cancer progression via MTDH interaction through the SESN2/AMPK/mTOR axis

SREBF1-mediated SND1 transcriptional activation promotes prostate cancer progression via MTDH interaction through the SESN2/AMPK/mTOR axis

Abstract Background Prostate cancer (PCa) is a prevalent cancer and a major cause of cancer-related deaths in men worldwide. Growing evidence indicates that Staphylococcal nuclease and Tudor domain containing 1 (SND1) is a multifunctional protein extensively involved in transcriptional regulation, R...

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Main Authors: Yijie Tang, Yufan Ying, Xueyou Ma, Jiahe Yi, Zixiang Liu, Yuqing Wu, Shen Lin, Xuan Shu, Zhixiang Qi, Jindan Luo, Xiangyi Zheng, Jiangfeng Li, Liping Xie, Ben Liu
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Journal of Translational Medicine
Subjects:
Prostate cancer
SND1
MTDH
SESN2
mTOR
Online Access:https://doi.org/10.1186/s12967-025-06762-2
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https://doi.org/10.1186/s12967-025-06762-2

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