Role of Bcr1-activated genes Hwp1 and Hyr1 in Candida albicans oral mucosal biofilms and neutrophil evasion.

Role of Bcr1-activated genes Hwp1 and Hyr1 in Candida albicans oral mucosal biofilms and neutrophil evasion.

Candida albicans triggers recurrent infections of the oropharyngeal mucosa that result from biofilm growth. Prior studies have indicated that the transcription factor Bcr1 regulates biofilm formation in a catheter model, both in vitro and in vivo. We thus hypothesized that Bcr1 plays similar roles i...

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Main Authors: Prabhat Dwivedi, Angela Thompson, Zhihong Xie, Helena Kashleva, Shantanu Ganguly, Aaron P Mitchell, Anna Dongari-Bagtzoglou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0016218&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0016218&type=printable

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