Human host defence peptide LL37 and anti-cyclic citrullinated peptide antibody in early inflammatory arthritis

Objective Antibodies to citrullinated peptides (anti-CCP) develop in individuals predisposed to rheumatoid arthritis (RA). Neutrophil extracellular traps are a major source of citrullinated antigens and the immunomodulatory host defence peptide LL-37. Vitamin D regulates LL-37 expression. This study...

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Bibliographic Details
Main Authors: Carol A Hitchon, Xiaobo Meng, Hani S El Gabalawy, Linda Larcombe
Format: Article
Language:English
Published: BMJ Publishing Group 2019-06-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/5/1/e000874.full
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