The solute carrier family 11 transporters: a bridge between iron homeostasis and tumor biology

The solute carrier family 11 transporters: a bridge between iron homeostasis and tumor biology

Abstract Iron is an essential trace element in the human body, and its imbalance is closely linked to the initiation and progression of various malignancies. The solute carrier family 11 (SLC11) transporters, comprising SLC11A1 and SLC11A2, play pivotal roles in iron metabolism and cellular homeosta...

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Main Authors: Ruchira Banerjee, Bintee Bintee, Mukesh Kumar Manickasamy, Shristy Jha, Mohammed S. Alqahtani, Mohamed Abbas, Arul Goel, Gautam Sethi, Zhaowu Ma, Ajaikumar B. Kunnumakkara
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cell Communication and Signaling
Subjects:
Iron
SLC11A1
SLC11A2
Iron transporters
Cancer
Online Access:https://doi.org/10.1186/s12964-025-02293-x
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https://doi.org/10.1186/s12964-025-02293-x

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