Performance Characterization and Validation of Saliva as an Alternative Specimen Source for Detecting Hereditary Breast Cancer Mutations by Next Generation Sequencing

Identification of pathogenic germline mutations by next generation sequencing is a widely accepted tool for predicting the risk of hereditary cancer development. Blood is the most common source of DNA for such tests. However, blood as a sample type has many drawbacks, including the invasive collecti...

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Bibliographic Details
Main Authors: Varsha Meghnani, Nadeem Mohammed, Christopher Giauque, Rahul Nahire, Thomas David
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:International Journal of Genomics
Online Access:http://dx.doi.org/10.1155/2016/2059041
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