Advances in the prerequisite and consequence of STING downstream signalosomes

The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway is an evolving DNA-sensing mechanism involved in innate immunity and pathogen defense that has been optimized while remaining conserved. Aside from recognizing pathogens through conserved motifs, these receptors also d...

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Bibliographic Details
Main Authors: Lu Xinliang, Li Xiaobing, Li Lili, Han Chuanhui, Li Sirui
Format: Article
Language:English
Published: De Gruyter 2024-10-01
Series:Medical Review
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Online Access:https://doi.org/10.1515/mr-2024-0016
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