Identification and isolation of human testicular peritubular myoid cells and Leydig cells by a combination of ITGA9 and NGFR

Identification and isolation of human testicular peritubular myoid cells and Leydig cells by a combination of ITGA9 and NGFR

Abstract Background Testicular somatic cells play an important role in supporting spermatogenesis. Leydig cells (LCs) and peritubular myoid cells (PTMs) originate from a common progenitor population and show similar expression signatures in adulthood, making it difficult to distinguish and isolate t...

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Main Authors: Sha Han, Liangyu Zhao, Jiaqiang Luo, Chenkun Shi, Chencheng Yao, Zhiyong Ji, Junwei Xu, Shuai Xu, Ruhui Tian, Erlei Zhi, Yuhua Huang, Xin Liu, Yuchuan Zhou, Zhi Zhou, Zheng Li, Peng Li
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Reproductive Biology and Endocrinology
Subjects:
ITGA9
NGFR
Testicular peritubular myoid cells
Adult Leydig cells
Online Access:https://doi.org/10.1186/s12958-025-01389-w
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https://doi.org/10.1186/s12958-025-01389-w

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