Modulation of Paracetamol-Induced Hepatotoxicity by Acute and Chronic Ethanol Consumption in Mice: A Study Pilot

Modulation of Paracetamol-Induced Hepatotoxicity by Acute and Chronic Ethanol Consumption in Mice: A Study Pilot

Paracetamol (APAP) overdose is the leading cause of drug-induced liver injury, leading to acute liver failure. However, the role of concurrent acute or chronic ethanol ingestion in this context requires further clarification. In this study, we investigated the effects of acute and chronic ethanol in...

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Main Authors: Allan Cristian Gonçalves, Aline Meireles Coelho, Maria Laura da Cruz Castro, Renata Rebeca Pereira, Natalia Pereira da Silva Araújo, Flávia Monteiro Ferreira, Pedro Alves Machado Júnior, Sirlaine Pio, Camilo Elber Vital, Frank Silva Bezerra, André Talvani, William de Castro Borges, Emerson Cruz de Oliveira, Daniela Caldeira Costa
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Toxics
Subjects:
paracetamol
acetaminophen
ethanol
alcohol
oxidative stress
hepatotoxicity
Online Access:https://www.mdpi.com/2305-6304/12/12/857
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