Glucuronolactone improves lung injury caused by PRRSV and DON co-challenge by enhancing the Nrf2-mediated antioxidant capacity in weaning piglets

Glucuronolactone improves lung injury caused by PRRSV and DON co-challenge by enhancing the Nrf2-mediated antioxidant capacity in weaning piglets

Abstract In the pig industry, both deoxynivalenol (DON) challenge and porcine reproductive and respiratory syndrome virus (PRRSV) infection can negatively impact the growth performance of pigs, thereby impairing the healthy development of the industry. Glucuronolactone (GLU) has been shown to be a p...

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Main Authors: Jing Hou, Chenbin Cui, Jing Wu, Min Tian, Qi Lu, Shilong Liu, Guohao Ye, Chaoyang Tian, Jiaxi Tang, Kaiguo Gao, Li Wang, Zongyong Jiang, Yueqin Qiu, Xuefen Yang
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Veterinary Research
Subjects:
Glucuronolactone
deoxynivalenol
PRRSV
oxidative stress
lung injury
Nrf2
Online Access:https://doi.org/10.1186/s13567-025-01596-8
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https://doi.org/10.1186/s13567-025-01596-8

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