Iterative selection of lipid nanoparticle vaccine adjuvants for rapid elicitation of tumoricidal CD8⁺ T cells

A challenge for cancer vaccines is to elicit immune responses of sufficient magnitude to control malignant tumor growth and spread. In this study, we iteratively screened a panel of 22 lipid-phase vaccine adjuvants in mice for the elicitation of neoantigen-specific CD8⁺ T cell responses, using an in...

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Bibliographic Details
Main Authors: Yuan Luo, Shiqi Zhou, Yiting Song, Wei-Chiao Huang, Gregory E. Wilding, James Jablonski, Breandan Quinn, Jonathan F. Lovell
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-06-01
Series:Bioactive Materials
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X25000283
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