A dual inhibitor of TrxR1 and XIAP induces pyroptosis in melanoma

Malignant melanoma ranks among the most aggressive forms of cancer, with high rates of metastasis and recurrence, as well as a poor prognosis. Consequently, an urgent need is to develop novel precision therapeutic strategies and corresponding drugs. Previous studies have shown that both X-linked inh...

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Bibliographic Details
Main Authors: Yuan Wang, Xiangmei Li, Xinyue Dong, Haokun Yuan, Ruiqin Fang, Ran Zhang, Wei-jia Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1542356/full
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