Marked elevation of circulating CD19+CD38hiCD24hi transitional B cells give protection against neonatal sepsis

Marked elevation of circulating CD19+CD38hiCD24hi transitional B cells give protection against neonatal sepsis

Adequate functions of immunoregulation, mediated by regulatory cells such as IL-10 producing CD19+CD38hiCD24hi transitional B cells (Trans), play an important role in control of excessive inflammatory response. Yet, the role of Trans in neonatal sepsis is incompletely understood. We investigated the...

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Bibliographic Details
Main Authors: Sitao Li, Fei Ma, Hu Hao, Desheng Wang, Yu Gao, Jialiang Zhou, Fei Li, Hung-Chih Lin, Xin Xiao, Qiyi Zeng
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Pediatrics and Neonatology
Subjects:
IL-10
late-onset sepsis
neonatal immunity
transitional B cells
Online Access:http://www.sciencedirect.com/science/article/pii/S1875957217302735
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