Intestinal epithelial cell NCoR deficiency ameliorates obesity and metabolic syndrome

Intestinal epithelial cell NCoR deficiency ameliorates obesity and metabolic syndrome

Nuclear receptor corepressor (NCoR1) interacts with various nuclear receptors and regulates the anabolism and catabolism of lipids. An imbalance in lipid/energy homeostasis is also an important factor in obesity and metabolic syndrome development. In this study, we found that the deletion of NCoR1 i...

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Main Authors: Shaocong Hou, Hengcai Yu, Caihong Liu, Andrew M.F. Johnson, Xingfeng Liu, Qian Jiang, Qijin Zhao, Lijuan Kong, Yanjun Wan, Xiaowei Xing, Yibing Chen, Jingwen Chen, Qing Wu, Peng Zhang, Changtao Jiang, Bing Cui, Pingping Li
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Nuclear receptor co-repressor 1
Intestinal epithelium
Metabolic syndrome
PPAR alpha
Liver X receptor
Thermogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383524003848
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