From sequence to protein structure and conformational dynamics with artificial intelligence/machine learning

The 2024 Nobel Prize in Chemistry was awarded in part for de novo protein structure prediction using AlphaFold2, an artificial intelligence/machine learning (AI/ML) model trained on vast amounts of sequence and three-dimensional structure data. AlphaFold2 and related models, including RoseTTAFold an...

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Bibliographic Details
Main Authors: Alexander M. Ille, Emily Anas, Michael B. Mathews, Stephen K. Burley
Format: Article
Language:English
Published: AIP Publishing LLC and ACA 2025-05-01
Series:Structural Dynamics
Online Access:http://dx.doi.org/10.1063/4.0000765
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