Validation of the SCID-hu Thy/Liv mouse model with four classes of licensed antiretrovirals.

Validation of the SCID-hu Thy/Liv mouse model with four classes of licensed antiretrovirals.

<h4>Background</h4>The SCID-hu Thy/Liv mouse model of HIV-1 infection is a useful platform for the preclinical evaluation of antiviral efficacy in vivo. We performed this study to validate the model with representatives of all four classes of licensed antiretrovirals.<h4>Methodolog...

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Main Authors: Cheryl A Stoddart, Cheryl A Bales, Jennifer C Bare, George Chkhenkeli, Sofiya A Galkina, April N Kinkade, Mary E Moreno, José M Rivera, Rollie E Ronquillo, Barbara Sloan, Paul L Black
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-08-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0000655&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0000655&type=printable

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