The PRINCIPLE randomised controlled open label platform trial of hydroxychloroquine for treating COVID19 in community based patients at high risk

The PRINCIPLE randomised controlled open label platform trial of hydroxychloroquine for treating COVID19 in community based patients at high risk

Abstract Early on in the COVID-19 pandemic, we aimed to assess the effectiveness of hydroxychloroquine on reducing the need for hospital admission in patients in the community at higher risk of complications from COVID-19 syndromic illness (testing was largely unavailable at the time, hence not micr...

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Bibliographic Details
Main Authors: F. D. Richard Hobbs, Jienchi Dorward, Gail Hayward, Ly-Mee Yu, Benjamin R. Saville, Christopher C. Butler, the PRINCIPLE Investigators
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Primary health care
SARS-COV-2
Serious COVID
Repurposed medicines
Hydroxychloroquine
Online Access:https://doi.org/10.1038/s41598-025-09275-6
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https://doi.org/10.1038/s41598-025-09275-6

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