Quercetin Reduces Antinociceptive but Not the Anti-Inflammatory Effects of Indomethacin, Ketorolac, and Celecoxib in Rats with Gout-like Pain

Quercetin Reduces Antinociceptive but Not the Anti-Inflammatory Effects of Indomethacin, Ketorolac, and Celecoxib in Rats with Gout-like Pain

The objective of this study was to determine the pharmacological interaction of some common NSAIDs in the presence of quercetin (QUER). Indomethacin (IND), ketorolac (KET), or celecoxib (CEL) were assessed alone and in combination with QUER using experimental gout-arthritic pain and the carrageenan-...

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Main Authors: José Aviles-Herrera, Guadalupe Esther Ángeles-López, Myrna Déciga-Campos, María Eva González-Trujano, Gabriel Fernando Moreno-Pérez, Ricardo Reyes-Chilpa, Irma Romero, Amalia Alejo-Martínez, Rosa Ventura-Martínez
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Molecules
Subjects:
gout pain
infra-additive interaction
natural products
NSAIDs
quercetin
Online Access:https://www.mdpi.com/1420-3049/30/15/3196
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