Activation of the Staphylococcus aureus intramembrane sensing histidine kinase SaeS via intramembrane interaction with the bacterially encoded small protein ScrA
ABSTRACT Two-component systems represent a fundamental sense-response mechanism in bacterial cells and often play important roles in critical processes such as quorum sensing, antibiotic tolerance, and virulence. Much has been learned about the role/activity of response regulator proteins, and their...
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| Main Authors: | Marcus A. Wittekind, Ian R. Monk, Ryan W. Steere, Emily G. Sudnick, Donald Holzschu, Padraig Deighan, Timothy P. Stinear, Ronan K. Carroll |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2025-07-01
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| Series: | mBio |
| Subjects: | |
| Online Access: | https://journals.asm.org/doi/10.1128/mbio.01531-25 |
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