Mitigating Doxorubicin‐Induced Cardiotoxicity and Enhancing Anti‐Tumor Efficacy with a Metformin‐Integrated Self‐Assembled Nanomedicine

Mitigating Doxorubicin‐Induced Cardiotoxicity and Enhancing Anti‐Tumor Efficacy with a Metformin‐Integrated Self‐Assembled Nanomedicine

Abstract Doxorubicin (Dox) is a potent chemotherapeutic agent commonly used in cancer treatment. However, cardiotoxicity severely limited its clinical application. To address this challenge, a novel self‐assembled nanomedicine platform, PMDDH, is developed for the co‐delivery of Dox and metformin, a...

Full description

Saved in:
Bibliographic Details
Main Authors: Jiaxin Huang, Jieru Yang, Yuanying Yang, Xiaofeng Lu, Juan Xu, Shan Lu, Hong Pan, Wenhu Zhou, Wenqun Li, Songwen Chen
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Advanced Science
Subjects:
cGAS‐STING
immunotherapy
mitochondrial dysfunction
nanoparticles
targeting
tumor therapy
Online Access:https://doi.org/10.1002/advs.202415227
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1002/advs.202415227

Similar Items