Parallel measurement of transcriptomes and proteomes from same single cells using nanodroplet splitting

Parallel measurement of transcriptomes and proteomes from same single cells using nanodroplet splitting

Abstract Single-cell multiomics provides comprehensive insights into gene regulatory networks, cellular diversity, and temporal dynamics. Here, we introduce nanoSPLITS (nanodroplet SPlitting for Linked-multimodal Investigations of Trace Samples), an integrated platform that enables global profiling...

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Main Authors: James M. Fulcher, Lye Meng Markillie, Hugh D. Mitchell, Sarah M. Williams, Kristin M. Engbrecht, David J. Degnan, Lisa M. Bramer, Ronald J. Moore, William B. Chrisler, Joshua Cantlon-Bruce, Johannes W. Bagnoli, Wei-Jun Qian, Anjali Seth, Ljiljana Paša-Tolić, Ying Zhu
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54099-z
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https://doi.org/10.1038/s41467-024-54099-z

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