Bering: joint cell segmentation and annotation for spatial transcriptomics with transferred graph embeddings

Abstract Single-cell spatial transcriptomics can provide subcellular resolution for a deep understanding of molecular mechanisms. However, accurate segmentation and annotation remain a major challenge that limits downstream analysis. Current machine learning methods heavily rely on nuclei or cell bo...

Full description

Saved in:
Bibliographic Details
Main Authors: Kang Jin, Zuobai Zhang, Ke Zhang, Francesca Viggiani, Claire Callahan, Jian Tang, Bruce J. Aronow, Jian Shu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60898-9
Tags: Add Tag
No Tags, Be the first to tag this record!