Nuclear Factor of Activated T Cells Is Activated in the Endothelium of Retinal Microvessels in Diabetic Mice

The pathogenesis of diabetic retinopathy (DR) remains unclear but hyperglycemia is an established risk factor. Endothelial dysfunction and changes in Ca2+ signaling have been shown to precede the onset of DR. We recently demonstrated that high extracellular glucose activates the Ca2+/calcineurin-dep...

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Main Authors: Anna V. Zetterqvist, Fabiana Blanco, Jenny Öhman, Olga Kotova, Lisa M. Berglund, Sergio de Frutos Garcia, Raed Al-Naemi, Maria Wigren, Paul G. McGuire, Laura V. Gonzalez Bosc, Maria F. Gomez
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2015/428473
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