Trehalose induces bladder smooth muscle hypercontractility in mice: involvement of oxidative stress and cellular senescence

Autophagy, a conserved catabolic process, is critical for cellular homeostasis and its dysregulation has been implicated in a number of conditions including hypertension, obesity and bladder dysfunctions. The autophagy inducer trehalose has shown promise in treating diseases; however, some studies h...

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Bibliographic Details
Main Authors: Guilherme Lemos, Cícera Madri Alves de Souza Fernandes, Ingrid Kazue Mizuno Watanabe, Maria Andreia Delbin, Fábio Henrique Silva, Fabiano Beraldi Calmasini
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Physiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1572139/full
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