Recombinant Enolase of Trypanosoma cruzi as a Novel Vaccine Candidate against Chagas Disease in a Mouse Model of Acute Infection

Trypanosoma cruzi is the protozoan parasite that causes Chagas disease, which is considered by the World Health Organization to be a neglected tropical disease. Two drugs exist for the treatment of Chagas disease, nifurtimox and benznidazole; they are only effective in the acute phase, and a vaccine...

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Main Authors: Minerva Arce-Fonseca, María Cristina González-Vázquez, Olivia Rodríguez-Morales, Verónica Graullera-Rivera, Alberto Aranda-Fraustro, Pedro A. Reyes, Alejandro Carabarin-Lima, José Luis Rosales-Encina
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2018/8964085
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