Truncated form of human CD19 antigen as a suicide gene to control T-cell alloreactivity: ΔCD19

Truncated form of human CD19 antigen as a suicide gene to control T-cell alloreactivity: ΔCD19

Donor lymphocyte infusion (DLI) is employed to either treat or prevent relapse in patients with hematologic malignancies, as well as to accelerate recovery of adaptive immunity, after allogeneic hematopoietic stem cell transplantation (allo-HSCT). With the increased use of DLI, there is renewed int...

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Main Authors: Simona Manni, Laura Iaffaldano, Marika Guercio, Pietro Merli, Francesca Del Bufalo, Marco Becilli, Mattia Algeri, Daria Pagliara, Rita De Vito, Gerhard Zugmaier, Biagio De Angelis, Concetta Quintarelli, Franco Locatelli
Format: Article
Language:English
Published: Ferrata Storti Foundation 2025-04-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/12050
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https://haematologica.org/article/view/12050

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