Identification of Prognostic Biomarkers of Ovarian High-Grade Serous Carcinoma: A Preliminary Study Using Spatial Transcriptome Analysis and Multispectral Imaging

Identification of Prognostic Biomarkers of Ovarian High-Grade Serous Carcinoma: A Preliminary Study Using Spatial Transcriptome Analysis and Multispectral Imaging

Ovarian cancer is a lethal malignancy, with most patients initially responding to chemotherapy but frequently experiencing recurrence. Previous studies primarily examined tumor characteristics using limited genetic markers or bulk RNA sequencing. Here, we used spatial transcriptomics via the GeoMx&l...

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Bibliographic Details
Main Authors: Haeyoun Kang, Je-Gun Joung, Hyun Park, Min Chul Choi, Doohyun Koh, Ju-Yeon Jeong, Jimin Lee, Sook-Young Kim, Daun Jung, Sohyun Hwang, Hee Jung An
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Cells
Subjects:
ovarian cancer
biomarkers
spatial transcriptomics
cancer recurrence
tumor microenvironment
Online Access:https://www.mdpi.com/2073-4409/14/10/681
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