Foxa2-dependent uterine glandular cell differentiation is essential for successful implantation

Abstract Uterine receptivity is essential for successful implantation. In mice, uterine receptivity begins with the secretion of LIF from uterine glands stimulated by estrogen on the morning of day 4 pregnancy. We hypothesize that gland readiness for estrogen stimulation is indispensable for uterine...

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Bibliographic Details
Main Authors: Zhaoyu Jia, Bo Li, Mitsunori Matsuo, Amanda Dewar, Anxhela Mustafaraj, Sudhansu K. Dey, Jia Yuan, Xiaofei Sun
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57848-w
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