Donor-Derived Cell-Free DNA Versus Left Ventricular Longitudinal Strain and Strain-Derived Myocardial Work Indices for Identification of Heart Transplant Injury

Donor-Derived Cell-Free DNA Versus Left Ventricular Longitudinal Strain and Strain-Derived Myocardial Work Indices for Identification of Heart Transplant Injury

<b>Background/Objectives:</b> Donor-derived cell-free DNA (dd-cfDNA) is a marker of graft injury that increases in acute rejection and has excellent negative predictive value. Left ventricular global longitudinal strain (LVGLS) and strain-derived myocardial work indices are novel echocar...

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Main Authors: Timea Teszak, Timea Barcziova, Csaba Bödör, Lajos Hegyi, Luca Levay, Beata Nagy, Attila Fintha, Adam Szijarto, Attila Kovacs, Bela Merkely, Balazs Sax
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Biomedicines
Subjects:
cardiac allograft rejection
donor-derived cell-free DNA
heart transplantation
left ventricular global longitudinal strain
myocardial work
Online Access:https://www.mdpi.com/2227-9059/13/4/841
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