Exploring the Mechanisms of the Antioxidants BHA, BHT, and TBHQ in Hepatotoxicity, Nephrotoxicity, and Neurotoxicity from the Perspective of Network Toxicology

Exploring the Mechanisms of the Antioxidants BHA, BHT, and TBHQ in Hepatotoxicity, Nephrotoxicity, and Neurotoxicity from the Perspective of Network Toxicology

The widespread use of food additives, such as butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), and tert-butylhydroquinone (TBHQ), has raised concerns about their potential toxicity, especially their hepatotoxicity, nephrotoxicity, and neurotoxicity. This study explores the targets and...

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Bibliographic Details
Main Authors: Jing Ren, Ziang Li, Xiaofen Li, Lin Yang, Zhulin Bu, Yuhui Wu, Yuting Li, Shuosheng Zhang, Xianglong Meng
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Foods
Subjects:
BHA
BHT
TBHQ
hepatotoxicity
nephrotoxicity
neurotoxicity
Online Access:https://www.mdpi.com/2304-8158/14/7/1095
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https://www.mdpi.com/2304-8158/14/7/1095

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