Tumor-associated myeloid cells support murine T-ALL in the central nervous system via integrin signaling
Abstract: T-cell acute lymphoblastic leukemia (T-ALL) is a common pediatric malignancy, and central nervous system (CNS) involvement is associated with inferior prognoses. Here, we show that in the LIM-domain-only-2 transgenic and LN3 mouse models of T-ALL, leukemia blasts infiltrate the CNS, where...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-08-01
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| Series: | Blood Neoplasia |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2950328025000305 |
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